About the Hao Lab

The Hao laboratory combines quantitative single-cell imaging, microfluidic technology and computational modeling to study how molecular networks govern regulatory responses in the context of stresses, aging, or diseases.

In particular, our current work focuses on:(1) decoding the dynamics of stress responses; (2) probing the causes of cellular aging; and (3) quantifying the heterogeneity in cancer cells.

We aim at building a research environment that enables a close coupling between experiment and theory and fosters the expansion of scientific expertise of each member in the laboratory.

Positions Available

    The laboratory currently has positions available for graduate students and postdoctoral fellows.

    We welcome applications from individuals with a solid background in biology, physics, or bioengineering, and a strong interest in developing a scientific career in quantitative systems biology.

    People with experience on mammalian cell culture are especially encouraged to apply.

What’s New

7.21 2020

Our Science paper made the front page of CNN! Congrats to Yang and the aging team!

7.16 2020

Our paper about the landscape of single-cell aging is published in Science. Congrats again to Yang and the aging team!

5.13 2020

Our paper about the landscape of single-cell aging is accepted for publication in Science. Congrats to Yang and the aging team!

4.27 2020

Our paper about PKA-mediated biphasic cellular memory is accepted for publication in Science Signaling. Congrats to Yanfei, Zohreh and Yutian!

4.6 2020

Bingxian gets the offer from Northwestern University. Congratulations!

4.11 2019

Yutian gets an offer from Caltech. Guoyu gets an offer from Yale. Congratulations!

3.6 2019

Our paper about divergent aging of isogenic cells is published in Cell Systems. Congrats to Meng and the aging team!

8.17 2018

Beverly has been selected for the 2018 Ruth Stern award. Congrats to Beverly!

8.6 2018

Welcome graduate student Andres Nevarez to the lab.

7.2 2018

Welcome graduate student Beverly Naigles to the lab.

5.7 2018

Nan has been promoted to Associate Professor with tenure!

4.7 2018

Julie has been selected for the 2018 AWIS Scholarship. Congrats to Julie!

11.9 2017

Our paper about single-cell MAPK dynamics is accepted for publication in JBC. Congrats to Yang, Julie and Zohreh!

11.2 2017

Our PNAS paper about silencing and aging has been featured on UCSD News and many other news outlets. Congrats to the aging team!

9.4 2017

Our paper about chromatin silencing dynamics during aging is accepted for publication in PNAS. Congrats to Yang!

8.8 2017

Zohreh has sucessfully defeneded her thesis. She is the first Ph.D. student from the lab. Congrats to Dr. AkhavanAghdam!

7.31 2017

We've been awarded an NIH multi-PI R01 to study Systems Biology of Aging. Nan is the Lead PI.

7.9 2017

Our paper about reconstructing the pheromone network (with Luo lab @PKU) is accepted for publication in PLoS Computational Biology.

6.21 2017

Our paper about feedback control of Msn2 dynamics is accepted for publication in JBC. Congrats to Yanfei and Zohreh!

9.30 2016

Our paper about paralog transcription factors is published in eLife. Congrats to Zohreh, Joydeb and Omar!

9.19 2016

Sorn gets the best TA award. Congrats to Sorn!

9.19 2016

Zohreh gets the best oral presentation award in the biology retreat. Congrats to Zohreh!

5.15 2016

We've been awarded an NSF grant to study synthetic biology of aging.

3.30 2016

Our lab moves to Bonner Hall.

3.9 2016

Joydeb gets an offer from Stanford. Congratulations!

1.11 2016

Welcome graduate student Julie Roberts to the lab.

6.22 2015

Welcome BS/MS student Gavin Shih to the lab.

4.10 2015

Welcome undergraduate Nina Escueta to the lab.

4.8 2015

Welcome graduate student Anusorn Mudla to the lab.

2.1 2015

Welcome postdoc Omar Tabbaa to the lab.

8.15 2014

We've been awarded an NIH R01 grant to study the dynamics of transcriptional regulation.

6.15 2014

Welcome postdoc Yang Li to the lab.

6.1 2014

Welcome BS/MS student Joydeb Sinha and Bioengineering undergraduate Jonathan Gan to the lab.

10.15 2013

Welcome undergraduates Ali Al Madhhachi and Laya Dasari to the lab.

10.1 2013

Welcome graduate student Zohreh AkhavanAghdam to the lab.

8.1 2013

The Hao lab starts at UCSD.